This is the companion web site for the following paper:


Alignment-Free Local Structural Search by Writhe Decomposition

Degui Zhi, Maxim Shatsky, and Steven E. Brenner, submitted.


writher is a system for rapid local structural search. This distribution contains a set of programs implementing the writhe decomposition algorithm and its associated database querying algorithms.


The writher manuscript [available upon journal acceptance] describes the writher algorithm and results of testing writher versus other fast structural comparison methods.


The writher code is distributed under the Affero General Public License Version 3 (AGPLv3).


Benchmarking data set:

Single domain test: scop_165_40.txt.

Multi-domain test: scop_165_40_md.txt.